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BIF401 Assignment No.01 Fall 2021 Solution / Discussion Due Date: 12-12-2021

Department of Bioinformatics and Computational Biology BIF401 – Bioinformatics – I

Assignment # 01 (Total Marks: 20)

Fall 2021

 

Due Date: 12th December2021

 

Instructions to be followed:

  • Your assignment should be submitted as MS Word/Pdf document
  • There is a Zero-Tolerance policy for plagiarism. Strict action will be taken in this regard.
  • Submit your assignment on VU LMS Portal within the given time frame. Email assignments will not be

 

Question # 1:

Part (a) – (2.5 Marks) [Word Limit: 200]

Which types of issues/problems related to biological data are dealt with the “Bioinformatics”?

 

Part (b) – (2.5 Marks)

Which alignment method is most suited to align closely related sequences? Explain in detail (Hint: Lesson # 32 – 48)

 

Question # 2: (10 Marks)

Find the best global alignment, and its corresponding score between the sequences,

Sequence γ = CAATAC and Sequence β = TCGTC. Use a match score of 5, a mismatch score of -5 and a gap penalty of -5. Show your work and fill the given Matrix.

(Hint: Lesson # 35 – 40)

 

 

 

T

C

G

T

C

 

0

 

 

 

 

 

C

 

 

 

 

 

 

A

 

 

 

 

 

 

A

 

 

 

 

 

 

T

 

 

 

 

 

 

A

 

 

 

 

 

 

C

 

 

 

 

 

 

 

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BIF401 Assignment No.01 Fall 2021 Solution File link 

BIF401-Assignment-01-Solution-Fall-2021_VU_Ning.pdf

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